제3그룹
송수정 교수 (3그룹책임)순천향대학교 의과대학 임상약리학교실
주요 연구 키워드
- 대사질환
- 비만
Contact
- 2014년 순천향대학교 조교수 부임
1. IK Vila, MK Park, SR Setijono, Y Yao, H Kim, PM Badin, S Choi, V Narkar, SW Choi, J Chung, C Moro, MS Song*, SJ Song*. A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity. JCI Insight. 2019 Jul;4(13). DOI: 10.1172/jci.insight.128269
2. MK Park, Y Yao, W Xia, SR Setijono, JH Kim, IK Vila, H Chiu, Y Wu, E González Billalabeitia, MG Lee, RG Kalb, M Hung, PP Pandolfi, MS Song*, SJ Song*. PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression. Nature Communications. 2019. Feb;10(1):636. DOI: 10.1038/s41467-019-08481-x
3. SR Setijono, MK Park, G Kim, Y Kim, KW Cho, SJ Song. miR-218 and miR 129 Regulate Breast Cancer Progression by Targeting Lamins. Biochem Biophys Res Commun. 2018 Feb;496(3):826–833 DOI: 10.1016/j.bbrc.2018.01.146
4. IK Vila, Y Yao, G Kim, W Xia, H Kim, SJ Kim, MK Park, JP Hwang, E González-Billalabeitia, MC Hung, MS Song*, SJ Song*. A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy. Cancer Cell. 2017 Feb;31(2):208224. DOI: 10.1016/j.ccell.2017.01.003 (Cover Story of February issue on Cancer Cell)
5. SJ Song, L Poliseno, MS Song, U Ala, K Webster, C Ng, G Beringer, NJ Brikbak, X Yuan, LC Cantley, AL Richardson, PP Pandolfi. MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling. Cell. 2013 Jul;154(2):311–324. DOI: 10.1016/j.cell.2013.06.026
6. SJ Song*, K Ito*, U Ala, L Kats, K Webster, SM Sun, M Jongen-Lavrencic, K Manova-Todorova, J Teruya-Feldstein, DE Avigan, R Delwel, PP Pandolfi. The Oncogenic MicroRNA miR-22 Targets the TET2 Tumor Suppressor to Promote Hematopoietic Stem Cell Self-Renewal and Transformation. Cell Stem Cell. 2013 Jul;13(1):87–101. DOI: 10.1016/j.stem.2013.06.003(Cover Story of February issue on Cell Stem Cell)
- 유방암, 전립선암에서 유비퀴틴 효소인 UBE20-AMPK-mTOR 활성에 의한 암대사 조절기전 규명
- 전립선암에서 Deubiquitinating 효소인 USP11에 의한 PTEN의 단백질 발현 조절 기전 규명
- 비만, 당뇨, 대사성질환에서 UBE20의 기능