연구진

  • 연구진

제2그룹

최동식 교수순천향대학교 의과대학 생화학교실

주요 연구 키워드

  • 프로테오믹스
  • 엑소좀
  • - POSTECH 생명과학과 박사

    - McGill대학교 Post Doc (엑소좀)

    - 순천향대학교 의과대학 생화학교실 조교수

    - 한국세포밖소포체학회 운영위원

     

  • 1. Extracellular vesicle communication pathways as regulatory targets of oncogenic transformation (2017, Seminars in cell & developmental biology (67, 11-22))

     

    2. Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumorderived extracellular vesicles (2018, Journal of Thrombosis and Haemostasis (16, 1800-1813))

     

    3. Molecular subtypes and differentiation programmes of glioma stem cells as determinants of extracellular vesicle profiles and endothelial cell-stimulating activities (2018, Journal of extracellular vesicles (7, 1490144))

     

    4. The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells (2018, Molecular & Cellular Proteomics (17, 1948-1964))

     

    5. Oncogenic regulation of extracellular vesicle proteome and heterogeneity (2019, Proteomics (19, 1800169))

     

    6. Mapping subpopulations of cancer cell-derived extracellular vesicles and particles by nano-flow cytometry (2019, ACS nano (13, 10499-10511))

     

    7. Extracellular VesicleMimetic Ghost Nanovesicles for Delivering Anti-Inflammatory Drugs to Mitigate Gram-Negative Bacterial Outer Membrane VesicleInduced Systemic Inflammatory Response Syndrome (2019, Advanced healthcare materials (8, 1801082))

     

    8. Extracellular vesicles as conduits of non-coding RNA emission and intercellular transfer in brain tumors (2019, Non-coding RNA (5, 1))

     

    9. A reference map of the human binary protein interactome (2020, Nature (580, 402-408))

     

    10. Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells (2020, Scientific reports (10, 1-14))

     

    11. Trastuzumab-induced upregulation of a protein set in extracellular vesicles emitted by ErbB2-positive breast cancer cells correlates with their trastuzumab sensitivity (2020, Breast Cancer Research (22, 1-16))

     

    12. Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo (2020, Stem cell research & therapy (11, 1-14))

     

    13. Quantitative proteomic analysis of trypsin-treated extracellular vesicles to identify the real-vesicular proteins (2020, Journal of extracellular vesicles (9, 1757209))

     

    14. Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles (2021, Blood Advances (5, 1682-1694))

     

    15. Isolation of extracellular vesicles for proteomic profiling (2021, Proteomic Profiling (193-206))

     

    16. Extracellular Vesicle Mediated Vascular Pathology in Glioblastoma (2021, Subcellular Biochemistry (97, 247-273))

     

    17. Oncogenic RAS drives the CRAFdependent extracellular vesicle uptake mechanism coupled with metastasis (2021, Journal of extracellular vesicles (10, e12091))

     

  • - 프로테옴 및 엑소좀 연구 19년(한국, 캐나다): 21편 주저자

    - J Extracell Vesicles (교신/IF 17.3) 

    - ACS Nano (제1/IF 18.0)

    - Mol Cell Proteomics (제1/IF 7.3)

    - Mass Spectrom Rev (제1/IF 9.0)

    - 박테리아 엑소좀 미세환경/면역활성/엑소좀 치료제 연구

     

  • - 한국세포밖소포체학회 신진연구자상 수상 (2022)