제2그룹
최동식 교수순천향대학교 의과대학 생화학교실
주요 연구 키워드
- 프로테오믹스
- 엑소좀
Contact
- POSTECH 생명과학과 박사
- McGill대학교 Post Doc (엑소좀)
- 순천향대학교 의과대학 생화학교실 조교수
- 한국세포밖소포체학회 운영위원
1. Extracellular vesicle communication pathways as regulatory targets of oncogenic transformation (2017, Seminars in cell & developmental biology (67, 11-22))
2. Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumor‐derived extracellular vesicles (2018, Journal of Thrombosis and Haemostasis (16, 1800-1813))
3. Molecular subtypes and differentiation programmes of glioma stem cells as determinants of extracellular vesicle profiles and endothelial cell-stimulating activities (2018, Journal of extracellular vesicles (7, 1490144))
4. The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells (2018, Molecular & Cellular Proteomics (17, 1948-1964))
5. Oncogenic regulation of extracellular vesicle proteome and heterogeneity (2019, Proteomics (19, 1800169))
6. Mapping subpopulations of cancer cell-derived extracellular vesicles and particles by nano-flow cytometry (2019, ACS nano (13, 10499-10511))
7. Extracellular Vesicle–Mimetic Ghost Nanovesicles for Delivering Anti-Inflammatory Drugs to Mitigate Gram-Negative Bacterial Outer Membrane Vesicle–Induced Systemic Inflammatory Response Syndrome (2019, Advanced healthcare materials (8, 1801082))
8. Extracellular vesicles as conduits of non-coding RNA emission and intercellular transfer in brain tumors (2019, Non-coding RNA (5, 1))
9. A reference map of the human binary protein interactome (2020, Nature (580, 402-408))
10. Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells (2020, Scientific reports (10, 1-14))
11. Trastuzumab-induced upregulation of a protein set in extracellular vesicles emitted by ErbB2-positive breast cancer cells correlates with their trastuzumab sensitivity (2020, Breast Cancer Research (22, 1-16))
12. Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo (2020, Stem cell research & therapy (11, 1-14))
13. Quantitative proteomic analysis of trypsin-treated extracellular vesicles to identify the real-vesicular proteins (2020, Journal of extracellular vesicles (9, 1757209))
14. Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles (2021, Blood Advances (5, 1682-1694))
15. Isolation of extracellular vesicles for proteomic profiling (2021, Proteomic Profiling (193-206))
16. Extracellular Vesicle Mediated Vascular Pathology in Glioblastoma (2021, Subcellular Biochemistry (97, 247-273))
17. Oncogenic RAS drives the CRAF‐dependent extracellular vesicle uptake mechanism coupled with metastasis (2021, Journal of extracellular vesicles (10, e12091))
- 프로테옴 및 엑소좀 연구 19년(한국, 캐나다): 21편 주저자
- J Extracell Vesicles (교신/IF 17.3)
- ACS Nano (제1/IF 18.0)
- Mol Cell Proteomics (제1/IF 7.3)
- Mass Spectrom Rev (제1/IF 9.0)
- 박테리아 엑소좀 미세환경/면역활성/엑소좀 치료제 연구
- 한국세포밖소포체학회 신진연구자상 수상 (2022)